REFACED Sepsis

Title

REFACED Sepsis

Aim

To test if an IV fluid restrictive protocol in ED patients with sepsis is feasible, i.e., if the protocol decreases the IV fluid volumes administered. tration.

Design

An investigator-initiated, multicenter, randomized, parallel-group, open-labeled, feasibility trial investigating volumes of fluid within 24 hours in 124 patients with sepsis allocated to two different IV fluid regimens enrolled at three emergency departments in Central Region Denmark: either standard care arm or fluid-restrictive arm.

Setting

Aarhus University Hospital, Regional Hospital Randers and Regional Hospital Viborg in Central Denmark Region. 

Population

Outcome

24-hour intravenous crystalloid fluid administration       

Collaborators

Aarhus University Hospital, Randers Regional Hospital and Viborg Regional Hospital.