REFACED Sepsis
To test if an IV fluid restrictive protocol in ED patients with sepsis is feasible, i.e., if the protocol decreases the IV fluid volumes administered. tration.
An investigator-initiated, multicenter, randomized, parallel-group, open-labeled, feasibility trial investigating volumes of fluid within 24 hours in 124 patients with sepsis allocated to two different IV fluid regimens enrolled at three emergency departments in Central Region Denmark: either standard care arm or fluid-restrictive arm.
Aarhus University Hospital, Regional Hospital Randers and Regional Hospital Viborg in Central Denmark Region.
24-hour intravenous crystalloid fluid administration
Aarhus University Hospital, Randers Regional Hospital and Viborg Regional Hospital.